… synthetic vaccine nanoparticles (SVNPs) that efficiently targeted lymph nodes, where immune
… antigens are primed, were developed to enhance antitumor immunity. The size (20–70 nm…

… Here, we discuss the development of nanoparticle vaccine (… lymph node targeting, antigen
presentation, and stimulation of … that boost anti-tumor immunity to synergize with immune …

… nanoparticle delivery to lymph nodes: (1) direct lymph node … surface will enhance B cell
activation by triggering multiple B … PhD in Immunology on the development of synthetic vaccine …

… inhibits and eliminates cancer by activating the immune system. … vaccines to reactivate
antitumor immune response and … or chemical synthesis, achieve the specific targeting with locally …

… defense against pathogens and antitumor immunity and “M2” … a productive activating immune
response. Importantly, once … Nanoparticle targeting of adjuvants to lymph nodes can thus …

… ) potentiates existing antitumor immune responses and induces … When tumor-draining lymph
nodes (TDLN) were targeted by … in draining lymph nodes and triggered strong CD8+ T-cell …

… by targeting nanovaccines to tumor-draining lymph nodes … microbubbles to allow
ultrasound-triggered transfection of DCs. … designed to elicit anti-tumoral immune responses. In …

… of tumor antigens as immune targets while exploiting … to lymph nodes, generating strong
antitumor T cell immunity. … able to elicit antitumor immunity against disseminated tumors…

… microenvironment to enhance antitumor immunity. Such … ) in lymph nodes, the tumor immune
microenvironment and … triggering potent macrophage-related anti-tumor immune responses…

… aims to activate or enhance the patient's adaptive immune system to kill tumor … Treatment
with immune cell-activating adjuvant without co-… Nanoparticle synthesis and characterization …